Friday, February 24, 2012

Jennifer Aniston

Absurdity of Jennifer Aniston: Let me first say something nice about Jennifer Aniston before the garbage to her: She has a beautiful body, it has proven itself to be a decent place, and I thought they proved their act well in the movie exactly one: "The Good Girl." But like all Hollywood idiots, it's the color of the left.
My husband has a theory that the actors in Hollywood lack of purpose. They know that what they do for a living - pretend - adds little to American society (except to provide great entertainment), they are painfully aware that their power is ridiculous. Can be their strength can not compare to good people, for example, or other people who are doing something useful with their lives.
So when Hollywood babe like Aniston come out and say something stupid, as I did last week - Click here - it is not surprising. Most of the representatives in Hollywood live in a bubble and zero understanding of reality. Should remain closed their mouths when dealing with the real world.
When I was a teacher, Bearing in mind the very positions of power, and thus careful about the types of things I said. And the power of a teacher on a much smaller energy than actors in Hollywood. For this reason, it is imperative that more of these guys talk as little as possible outside their work environment - unless they have something smart (ie, conservatives) to say that adds, rather than decrease, in the community.
Motherhood and to encourage one by choice is the dumbest thing a woman can argue. Aniston does not have the statistics on her side - most of today's social problems (drug abuse, and mixing, and cases of unwanted pregnancy, school dropouts, runaways, suicide, and crime) are the result of children being raised without biological fathers. Chances are, it's not even aware of the statistics.
In fairness to Ms. Aniston, has been raised in the culture of feminism. Consider these comments from other women of the influential liberal: Comments such as these record prices in the media. Left reduces women to men routinely and increasingly dismissive of the critical role they play in society. Why? For as smart Gretchen Carlson proposed to Bill O'Reilly, Aniston and bitter. Her personal life did not work out the way he wants, and even now she needs to make a political statement.
This is what all women are dissatisfied with the liberal do. This is what married miserably Betty Friedan (she and her former husband, Carl Friedan and physically abusive mentally in the direction of one another) was compared with motherhood is a "concentration camp comfortable", and set out to change America, rather than dealing with her own limitations and personal circumstances.
Aniston has followed suit. Rather than accepting there may be something wrong with her vision or understanding of marriage and relationships, and insisted on family life and "evolved" and says that women should not "fiddle with a man" to have a child. Feminist Friedan takes to a whole new level. Stick to your hats, and men of America. Women on the left are just starting out - they're after is a matriarchy.

Superhero Bridesmaids

Heart Tattoo Designs

Heart tattoo designs are perfect for those who want to express their love and emotions through the art of the body. There are various designs of the heart that carry different meanings, and the importance of holding different.
The heart is the symbol that represents love and wisdom. Has been used in different eras fan of this symbol to express their love. In today's modern era, and people use this art to express their feelings about tattoos. Heart Tattoos are very common among people who want to show love and sympathy with their friends, family and others of their own.
Although often considered a symbol of eternal love, tattoos heart and many other changes depending on the subject. There are many tattoo heart that have different meanings. For example, while the Flaming heart tattoo shows passionate love, and love heart with an arrow means beaten.
Heart Tattoos so popular that many celebrities have been up to this tattoo design in the sports body. Some famous personalities that have monitored with heart tattoo Lindsay Lohan, Mandy Moore, Julia Roberts and many others.


Like most scientists and doctors in this area, I chose a career developing drugs in the hope of improving people's lives. 'Hope' I say, because pharmaceutical research and development is often a source of frustration and disappointment. Certainly, we are continuing contribution to the scientific and medical knowledge, but our work does not always result in new drugs. Very few to get one of us to work on vehicles that ultimately benefit patients.
I was one of those fortunate though. In the two decades of research, I have managed to be in the right place at the right time in more than one occasion. But the development program has been a greater interest and participation in one of the drugs in the world's most famous. Scientific name is sildenafil citrate, but it is better known as Viagra.
I first came across this project in the late 1980s, when I learned colleagues in

the laboratories of Pfizer in Sandwich, a small town on the southeastern coast of England, has come up with a hypothesis about the prohibition of selective enzyme called PDE5. They believed they could produce a drug to prevent PDE5 can expand blood vessels and treatment of angina pectoris. While the purpose of the project was fantastic, and I must admit I was doubtful it would be a breakthrough because they had hoped.
By the early 1990s, and was the team discovered a strong and selective inhibitor of PDE5, known at that time in the United Kingdom 92 480. Tests showed early had a moderate impact on the blood vessels of healthy volunteers, which was promising sign. However, only inhibitor in the body for a relatively short period, and when taken three times a day - to maintain a constant effect - it gave some pain in the muscles of volunteers.

In one of the studies, and volunteers for male erectile dysfunction increased after several days of the initial dose. No one thought of us at Pfizer many of these side effects at that time. I remember thinking that even if it did not work, who want to take the drug on Wednesday to get an erection on Saturday? We paid for it with studies in angina pectoris.
At the time I run one of two clinical trials, Pfizer, near Sandwich, where we

studied whether the United Kingdom 92 480 interacted with nitrates - standard treatment for angina. We found that it did not exaggerate the impact of nitrates, which may cause the blood pressure drops too much. This turned out to be one of the many results which reduced the likelihood of becoming the United Kingdom 92 480 treatment of angina pectoris.
However, it has now been increased erectile dysfunction reported in studies on volunteers more than that, so we decided to follow up on these reports to know that it will take us.
Incidentally, it was almost at the same time, other studies reveal more information about the path of biochemical participate in the erection process. This has helped to understand how the drug can amplify the effects of sexual stimulation in opening up the blood vessels in the penis. With opportunities in the United Kingdom 92 480 for the treatment of angina now slim, we decided to run pilot studies in patients who suffer from erectile dysfunction). In the preliminary study, and watch videos while the exciting device to monitor the ring and solid bars of their own. Initial results were encouraging and showed that the drug was more effective than placebo.
However, we have had there is still a long way to go and a lot of question marks. He said that the drug be effective when used in the preparation of less clinical and after a single dose? How can we measure its effects accurately without being intrusive? The work will be in men who suffer from ED due to various medical conditions, such as high blood pressure, diabetes, heart disease or prostate?

The next trial included more than 300 patients from the United Kingdom, Sweden and France.

We included men with diabetes, to extend the duration of treatment for four weeks and tested three different doses and placebo. Questioned by some doctors in this area that the drug through the mouth can be opened selectively in the blood vessels in the penis, but we persevered, and I remember a distinct air of excitement at the first meeting with the investigators - who were doctors adminstering drugs in the next trial.
It also provides for the trial, and I began to feel more and more nervous the possibility of knowledge of results - not least because we have now spent several millions of dollars on this project until now, was to deliver the drug for use. The investigators reported encouraging results, but to assume that most of these patients were on placebo? We have obtained the right dose? Will patients understand the drug works only with sexual stimulation? Do we have the questionnaires and diaries make it clear enough, and patients will complete correctly? I asked myself all these questions over and over again.
Statisticians in the team is the first to see the data - it's important to analyze the results and verify the figures. People are being careful, and they do not like to exchange information so they are quite confident of the results. I remember a desperate attempt to read the language of statistical our leadership in the body in the days before the results. But it was distinctive deadpan and I was able to deduce something from his behavior.
When the results came at the end of the day through it exceeded the wildest expectations we have. There was a correlation between dose and response beautiful, with about 90 per cent of patients responding at the highest dose. This drug was also well tolerated, with a very small number of patients reporting pain in the muscles and a very small number of school drop-out. Diaries and questionnaires also provided accurate results and consistent. Impossible not to feel the thrill and excitement at this stage of the study, and I'm not sure.
But the nature of drug development means that you can not taste the highest level for a long time. We were preparing to embark on the most expensive stage of drug development - clinical trials, long-term for thousands of patients in all parts of the world. This requires hundreds of millions of dollars - and we still did not get a chance and only one out of every five of the drug to pass these tests and obtain a license. Therefore, the company will continue to fund a project we have?
The program has already attracted some unexpected publicity, and I am concerned what impact this may have on this resolution. Fortunately, he had written a large number of those who suffer from impotence to us how the situation has had devastating effects on their relationships, and how they were desperate for effective treatment. These letters, and convinced us there is also an urgent need for the treatment of ED and encouraged us to continue to pay the program internally.
We have received funding from the outside and as we continue the clinical program and found the results were better and better. And worked well in the men drug with a variety of causes of ED, including diabetes and spinal cord injury. It also continued to be well tolerated.
12 years after the project began, eight years after the first synthesis of the year in the United Kingdom 92 480 and four after the pilot study the first ED, we had enough information and finally to be confident of the best dose, and drug safety and effectiveness. We applied for a license from the regulatory authorities in 1997.
The rest, as they say, is history. Are being prescribed Viagra for some men 30000000 in all parts of the world. It's very rewarding to see our work has benefited many people. It is this fact that makes the long days and frustration, which is an integral part of development, and drugs intolerable.
I would like to remind myself that I have just one member of a great team - in about 100 specialties of experts to have played a role in making Viagra available to patients. Like many successful scientists, I have had my fair share of luck.

Angels Tattoos of Girl

And one of the following important in the design of this tattoo is a tattoo tribal tattoos and this is very popular in these days. Most of these tribal tattoo designs are in accordance with tribal communities, and they reflect the myth and religion and values ​​in the tribal society. Celtic, Hawaii, Polynesian, Native American tattoo designs are the most important that the girls choice. If you want to show your love, then the heart tattoo is one of the best and this one is treated as a symbol of romantic love. Most of the girls interested in the tattoo design with the name of the beloved fireplace written across it. Butterfly tattoos, angel tattoos for girls and some other countries, it is important and popular. Finally, there are some well-established and experienced web sites that offer these ideas Girl Tattoo value to its customers.

Foot Tattoos

In general, we can see that the rate of our concern that an important part and a large part about the moves and plays from one place to another, so that the important issue, while the analysis of the female tattoo foot and in accordance with the spirit. Many people actually analyze and consider in his mouth, this place what is happening, and also get a tattoo as well. Thinking in this kind of small flower tattoo peeks also natural that the shoes that look very nice, as well as some slightly more attractive as well.
Here and there can be numerous events aimed If you use a girl foot tattoo especially for the majority of women. But day after day, the popularity of these aspects increase, so can be found on one of the details can be more easily about these things. Full design and can be used here is very simple and one can easily recognize the details as well. Remember in this popular item, while the design of all events, such as flowers, and different views, different fairies are the most popular form of tattoo designs so that these things are corrected on the basis of their importance. Now we must go to the following factors before we go any further, as follows:
Angel tattoo foot: This would be one of the female form of designs that can be used in the tattoo design female foot. Can be called to this scenario as protectors of the corner and take more spiritual, so these are all more than mirror our personalities and mind. But we must realize that the foot area so it may be small in that region as a whole, and we will get one or two angles, so it gives the agent behavior in full, while the analysis of the details as well.
Flower tattoos foot: This type of tattoo foot mutilation is always the best part as the best in their concerns and work in tattoo female from the overall design of care. These flowers have always stressed the importance and significance of certain evidence that much useful advice for most scenarios. Consideration to the prosperity of flower tattoos the only thing that can make many of the foot tattoo is great, so while the design of the blocks, and these are important aspects.
Fairy foot tattoo: It is one of the strongest aspects of a popular way to get a tattoo female, and thus the use of this type can be obtained as well as appearance fees, even those are the important aspect, while understanding the many other features. This kind of fairies and can be designed and drawn on a different way, so these things are a reflection of their personality as well as skills.
For women to cover the pros and mouth a little bit different aspect of design tattoo design works a lot so that the essential aspect, and understanding of these functions. The most important aspect about this is that tattoo foot tattoos do not want to expose to others, so that more secret about female tattoo foot.